This product has not been evaluated by SAHPRA. For information purposes only — not intended to diagnose, treat, cure or prevent any disease.
EnergyResearch vialcibinetideanti-inflammatorynerve repairneuropathyEPO-derived
ARA-290
Non-erythropoietic EPO fragment that targets the innate repair receptor on injured tissue
R 585
10mg vial
Innate repair receptorBinds the EPOR/CD131 heterocomplex on injured tissue
Anti-inflammatoryTriggers a pro-repair signalling cascade without raising red cells
Neuropathy dataReduced small fiber neuropathy symptom score in a sarcoidosis pilot
Metabolic signalLowered HbA1c by ~0.2% versus placebo in a T2D trial
ARA-290 (cibinetide) is an 11-amino-acid peptide engineered from the helix B region of erythropoietin. Unlike EPO it has no effect on red blood cell production — it binds the innate repair receptor (a heterocomplex of EPOR and CD131) on injured tissue, which triggers an anti-inflammatory and pro-repair signalling cascade. It holds FDA Orphan Drug designation for sarcoidosis-associated neuropathic pain.
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Regulatory
This product has not been evaluated by the South African Health Products Regulatory Authority (SAHPRA).
For information purposes only — not intended to diagnose, treat, cure or prevent any disease.