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Not evaluated by SAHPRA · Research & educational information only · Nothing on this site is for sale · Not medical advice · Consult a healthcare professional
Not evaluated by SAHPRA. Research & educational information only — nothing is for sale; not intended to diagnose, treat, cure or prevent any disease.
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Mind & MoodResearch vialanxietymoodgabanon-sedatingresearch

Selank

Tuftsin analogue for anxiety without sedation

Format
Research vial
Strength / pack
30mg vial
Category
Mind & Mood
Anxiolytic comparable to medazepamZozulia 2008 in 62 patients with GAD or neurasthenia: intranasal Selank matched oral medazepam on anxiety reduction.
Antiasthenic and mildly stimulatingUnlike benzodiazepines, produced antiasthenic and mild psychostimulant effects rather than sedation.
GABAergic without benzo toleranceCompetes for >50% of [3H]diazepam binding sites on rat brain membranes — supports GABAergic action without classic benzodiazepine tolerance or withdrawal.
Normalises enkephalin half-lifeCorrelated with normalised leu-enkephalin half-life in clinical work.
Selank is a synthetic heptapeptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro) developed at the Institute of Molecular Genetics in Moscow as a stabilised analogue of the immunomodulatory peptide tuftsin. It is registered as an anxiolytic in Russia. Proposed mechanisms include allosteric modulation of GABA-A receptors and modulation of brain enkephalin levels.
Publisher
Elegant Slimming · Mokopane, Limpopo, South Africa
Research library · nothing on this site is for sale.
Regulatory
This compound has not been evaluated by the South African Health Products Regulatory Authority (SAHPRA).
For information purposes only — not intended to diagnose, treat, cure or prevent any disease.